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bio_frontend/pages/test/pathway.vue

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Vue
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2025-09-12 11:10:43 +09:00
<template>
<div style="position: relative;">
<h2>KEGG Pathway Viewer (Compact Overlay)</h2>
<div ref="cyContainer" style="width: 100%; height: 800px; border: 1px solid #ccc; position: relative;"></div>
<div ref="overlayContainer" style="position: absolute; top: 0; left: 0; width: 100%; height: 100%; pointer-events: none; z-index: 1000;"></div>
</div>
</template>
<script setup>
import { ref, onMounted, nextTick } from 'vue'
import cytoscape from 'cytoscape'
import { Chart, registerables } from 'chart.js'
Chart.register(...registerables)
const cyContainer = ref(null)
const overlayContainer = ref(null)
const chartMap = new Map()
function toRenderedPosition(pos, cy) {
const zoom = cy.zoom()
const pan = cy.pan()
return {
x: pos.x * zoom + pan.x,
y: pos.y * zoom + pan.y
}
}
onMounted(async () => {
await nextTick()
const resizeOverlay = () => {
if (!cyContainer.value || !overlayContainer.value) return
overlayContainer.value.style.width = cyContainer.value.offsetWidth + 'px'
overlayContainer.value.style.height = cyContainer.value.offsetHeight + 'px'
}
resizeOverlay()
window.addEventListener('resize', resizeOverlay)
const res = await fetch('/pon00061.xml')
const xmlText = await res.text()
const parser = new DOMParser()
const xmlDoc = parser.parseFromString(xmlText, 'application/xml')
const scale = 5
const entryMap = new Map()
const entryDataMap = new Map()
const parentMap = new Map()
const entries = Array.from(xmlDoc.getElementsByTagName('entry'))
for (const entry of entries) {
const id = entry.getAttribute('id')
entryDataMap.set(id, entry)
if (entry.getAttribute('type') === 'group') {
const components = entry.getElementsByTagName('component')
for (const comp of components) {
const childId = comp.getAttribute('id')
parentMap.set(childId, id)
}
}
}
const nodes = entries.map(entry => {
const id = entry.getAttribute('id')
const graphics = entry.getElementsByTagName('graphics')[0]
const x = parseFloat(graphics?.getAttribute('x') || '0') * scale
const y = parseFloat(graphics?.getAttribute('y') || '0') * scale
const label = graphics?.getAttribute('name') || id
const fgColor = graphics?.getAttribute('fgcolor') || '#000000'
const bgColor = graphics?.getAttribute('bgcolor') || '#ffffff'
const entryType = entry.getAttribute('type')
const shapeType = entryType === 'compound' ? 'compound' : entryType === 'group' ? 'group' : entryType === 'ortholog' ? 'ortholog' : 'gene'
const parent = parentMap.get(id)
const node = {
data: {
id,
label,
link: entry.getAttribute('link') || null,
reaction: entry.getAttribute('reaction') || null
},
position: { x, y },
classes: shapeType,
style: {
color: fgColor,
'background-color': bgColor
}
}
if (parent) node.data.parent = parent
entryMap.set(id, true)
return node
})
function resolveToRealNode(id) {
if (!entryMap.has(id)) return null
const entry = entryDataMap.get(id)
if (entry?.getAttribute('type') === 'group') {
const components = Array.from(entry.getElementsByTagName('component'))
if (components.length > 0) return components[0].getAttribute('id')
}
return id
}
const edges = []
const relations = Array.from(xmlDoc.getElementsByTagName('relation'))
relations.forEach((rel, i) => {
let source = resolveToRealNode(rel.getAttribute('entry1'))
let target = resolveToRealNode(rel.getAttribute('entry2'))
const type = rel.getAttribute('type')
const subtypes = Array.from(rel.getElementsByTagName('subtype'))
const compoundSubtype = subtypes.find(s => s.getAttribute('name') === 'compound')
if (compoundSubtype) {
const compoundId = compoundSubtype.getAttribute('value')
if (entryMap.has(source) && entryMap.has(target) && entryMap.has(compoundId)) {
edges.push(
{ data: { id: `edge${i}-1`, source, target: compoundId, label: 'via compound' } },
{ data: { id: `edge${i}-2`, source: compoundId, target, label: 'via compound' } }
)
}
} else {
if (entryMap.has(source) && entryMap.has(target)) {
edges.push({ data: { id: `edge${i}`, source, target, label: type } })
}
}
})
const reactions = Array.from(xmlDoc.getElementsByTagName('reaction'))
reactions.forEach((reaction, i) => {
const reactionType = reaction.getAttribute('type')
const reactionLabel = reaction.getAttribute('name') || `reaction${i}`
const substrates = Array.from(reaction.getElementsByTagName('substrate'))
const products = Array.from(reaction.getElementsByTagName('product'))
substrates.forEach(substrate => {
const sid = resolveToRealNode(substrate.getAttribute('id'))
products.forEach(product => {
const pid = resolveToRealNode(product.getAttribute('id'))
if (entryMap.has(sid) && entryMap.has(pid)) {
edges.push({ data: { id: `reaction-${i}-${sid}-${pid}`, source: sid, target: pid, label: `${reactionLabel} (${reactionType})` } })
if (reactionType === 'reversible') {
edges.push({ data: { id: `reaction-${i}-${pid}-${sid}`, source: pid, target: sid, label: `${reactionLabel} (reversible)` } })
}
}
})
})
})
const cy = cytoscape({
container: cyContainer.value,
elements: { nodes, edges },
style: [
{ selector: 'node', style: { label: 'data(label)', 'text-valign': 'center', 'text-halign': 'center', shape: 'rectangle', 'font-size': 10, 'border-width': 1, 'border-color': '#333' } },
{ selector: '.ortholog', style: { 'background-color': '#ccffcc', shape: 'round-rectangle', 'border-width': 2, 'border-color': '#339933' } },
{ selector: '$node > node', style: { 'background-color': '#f3f3f3', 'border-width': 2, 'border-color': '#666', shape: 'roundrectangle' } },
{ selector: '.compound', style: { 'background-color': '#ffe135', shape: 'ellipse' } },
{ selector: 'edge', style: { width: 2, 'line-color': '#888', 'target-arrow-shape': 'triangle', 'label': 'data(label)', 'font-size': 8 } }
],
layout: { name: 'preset' }
})
cy.ready(() => {
cy.fit(cy.elements(), 100)
createNodeOverlays(cy)
})
cy.on('render', () => {
requestAnimationFrame(() => updateOverlayPositions(cy))
})
})
function createNodeOverlays(cy) {
cy.nodes().forEach(node => {
const pos = node.renderedPosition()
const id = node.id()
const wrapper = document.createElement('div')
wrapper.style.position = 'absolute'
wrapper.style.left = `${pos.x + 30}px`
wrapper.style.top = `${pos.y - 40}px`
wrapper.style.width = '20px'
wrapper.style.height = '80px'
wrapper.style.background = 'rgba(255,255,255,0.9)'
wrapper.style.fontSize = '6px'
wrapper.style.border = '1px solid #ccc'
wrapper.style.borderRadius = '2px'
wrapper.style.overflow = 'hidden'
wrapper.style.pointerEvents = 'none'
wrapper.style.zIndex = '9999' // 보장
const table = document.createElement('table')
table.style.borderCollapse = 'collapse'
table.style.width = '100%'
for (let i = 0; i < 7; i++) {
const tr = document.createElement('tr')
for (let j = 0; j < 2; j++) {
const td = document.createElement('td')
td.textContent = '·'
td.style.padding = '0'
td.style.fontSize = '6px'
td.style.textAlign = 'center'
tr.appendChild(td)
}
table.appendChild(tr)
}
const canvas = document.createElement('canvas')
canvas.width = 16
canvas.height = 16
canvas.style.margin = '2px auto 0'
canvas.style.display = 'block'
wrapper.appendChild(table)
wrapper.appendChild(canvas)
overlayContainer.value.appendChild(wrapper)
const ctx = canvas.getContext('2d')
const chart = new Chart(ctx, {
type: 'doughnut',
data: {
labels: ['A', 'B'],
datasets: [{ data: [30, 70], backgroundColor: ['#ff6384', '#36a2eb'] }]
},
options: {
responsive: false,
plugins: { legend: { display: false }, tooltip: { enabled: false } },
cutout: '60%',
animation: false
}
})
chartMap.set(id, { wrapper, chart })
})
}
function updateOverlayPositions(cy) {
cy.nodes().forEach(node => {
const entry = chartMap.get(node.id())
if (entry) {
const pos = node.renderedPosition()
entry.wrapper.style.left = `${pos.x + 30}px`
entry.wrapper.style.top = `${pos.y - 40}px`
}
})
}
</script>